Permanent damage to the penis may occur if priapism is not treated quickly.

Before Using

Its effect may last up to 36 hours.1,6 The dose can be increased to 20 mg if necessary. Safe dosing of tadalafil includes downward dosage adjustment to 5 mg in patients with moderate to severe renal insufficiency. In patients with mild to moderate hepatic dysfunction, the tadalafil dose should not exceed 10 mg. Tadalafil is not recommended in patients with severe hepatic dysfunction. Like other PDE5 inhibitors, tadalafil effectively improves the ability of men with erectile dysfunction to achieve an erection and successfully complete intercourse.

Professional resources

It is less effective, although still useful, in some men with ED due to diabetes. Its longer duration may require less frequent dosing and may allow the user to take it earlier in the day of planned sexual activity. However, some authorities suggest that, because the sildenafil safety record is more established, it may be preferred over tadalafil.4 Tadalafil is a medicine that is commonly used for the following conditions. Erectile dysfunction, a condition where you have trouble getting or keeping an erection Pulmonary arterial hypertension, a condition where you have high blood pressure in the blood vessels that carry blood from your heart to your lungs Benign prostatic hyperplasia (BPH), a condition where the prostate gland has become enlarged Tadalafil may also be used for other conditions as determined by your healthcare provider. Tadalafil works by blocking the activity of an enzyme called phosphodiesterase 5 (PDE5). Stop taking tadalafil and get emergency help right away if you have any of the following symptoms of priapism.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	2.5mg	10 Pills	28.51€ 27.15€
Cialis Original	20mg	8 Pills	61.70€ 58.76€
Cialis Generic	10mg	60 + 6 Pills	105.81€ 100.77€
Cialis Super Active	20mg	90 + 10 Pills	314.14€ 299.18€
Cialis Generic	2.5mg	20 Pills	40.73€ 38.79€
Cialis Generic	5mg	360 + 10 Pills	268.08€ 255.31€
Cialis Generic	2.5mg	90 + 6 Pills	112.43€ 107.08€
Cialis Black	80mg	60 + 4 Pills	150.98€ 143.79€
Cialis Professional	40mg	60 + 2 Pills	262.32€ 249.83€
Cialis Professional	20mg	10 Pills	48.29€ 45.99€
Cialis Generic	40mg	10 Pills	37.79€ 35.99€
Cialis Generic	5mg	180 + 10 Pills	159.65€ 152.05€
Cialis Professional	20mg	270 + 6 Pills	623.07€ 593.40€

Erection lasting for more than 4 hours Erection that is unrelated to sexual stimulation If you feel faint or dizzy, lie down.

Safety Infomation

This enzyme usually stops some types of muscles from relaxing, including the muscles lining some types of blood vessels. By blocking PDE5, the muscles will relax and blood flow increases. For erectile dysfunction, it increases blood flow to the penis when aroused. This makes it easier to get and keep an erection. For pulmonary arterial hypertension, tadalafil relaxes the blood vessels in the lungs.

Can women take Cialis?

This lowers blood pressure and reduces strain on cialis super aktiv the heart. For benign prostatic hyperplasia, tadalafil relaxes the muscles of the bladder and prostate, making it easier to urinate and reducing symptoms. Tadalafil should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. The most common side effects of tadalafil are listed below. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure. Tadalafil can cause mild, temporary vision changes such as seeing a blue tint, abnormal colors, blurry vision, or sensitivity to light.

Society and culture

The makers of these brands are not affiliated with and do not endorse Eli Lilly and Company or its products. Tadalafil is a reversible phosphodiesterase type 5 (PDE5) inhibitor approved for the treatment of erectile dysfunction (ED). As a class, PDE5 inhibitors (including sildenafil [Viagra] and vardenafil [Levitra]), enhance erectile response to sexual stimulation by increasing penile blood flow. In general, few side effects occur with tadala-fil unless it is taken in conjunction with other drugs. When combined with α1-adrenergic blockers such as doxazosin (Cardura), prazosin (Minipress), and terazosin (Hytrin) but not tamsulosin (Flomax)—tadalafil can cause a significant drop in blood pressure.

Why Should I Pay More For the Same Results?

Similarly, concomitant use of nitrates (including recreational nitrates known as “poppers”) with tadalafil also is contraindicated. For life-threatening situations, nitrates may be considered if at least 48 hours have passed since the last dose of tadalafil and if close hemodynamic monitoring is available. Tadalafil will lower blood pressure an additional 4 to 10 mm Hg when used with antihypertensive drugs. Dosage should be limited to 10 mg within a 72-hour period when patients are also taking drugs such as erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), protease inhibitors, and other drugs that inhibit the CYP3A4 enzyme system.1 Patients with cardiovascular diseases have been excluded from studies of tadalafil because so little is known about its safety profile in this population.1 The current recommendation for patients who experience coital angina after taking a PDE5 inhibitor is to contact emergency services that provide transport to a hospital.2 Rare reports of priapism have been reported with all of the drugs in this class.1 Long-term safety has not been established. Because of tadalafil’s long duration of action, patients are exposed to its effects for a longer period of time than with sildenafil or vardenafil.3,4 The most common dose-related side effects of tadalafil are headache (11 to 15 percent) and dyspepsia (8 to 10 percent). Though rare, some people have reported permanent vision loss. Stop taking tadalafil and get help right away if you have sudden vision loss in one or both eyes.

14.1 CIALIS for Use as Needed

Back pain, beginning 12 to 24 hours after the dose and lasting for up to 48 hours, was reported in 5 to 6 percent of men, as compared with a rate of 3 percent in men receiving placebo. Changes in color vision, which has been reported with sildenafil, has been reported in less than 0.1 percent of patients in clinical trials of tadalafil.1 Tadalafil differs from sildenafil in its affinity for PDE6 and 11, which may account for fewer reported ocular effects and more reports of back pain with tadalafil than with sildenafil.3 The main outcomes studied in the treatment of ED are achievement of an erection, successful intercourse, and overall satisfaction with sexual function. In five studies evaluating tadalafil in 5-, 10-, and 20-mg doses versus placebo, 321 men were assigned to a 10-mg regimen. In this group, 68 to 77 percent of men reported an erection suitable for insertion, compared with 42 to 55 percent receiving placebo (number needed to treat [NNT]=4 to 4.5). However, slightly fewer men reported successful intercourse (51 to 70 percent, NNT=4 to 5).1,5 The satisfaction with intercourse was 9.3 out of a maximum score of 15, compared with a score of 7.4 in patients taking placebo, and overall satisfaction was 6.7 out of a possible 10 with tadalafil compared with 5.2 in patients taking placebo.5 As with the other drugs in this class, overall effectiveness is diminished in patients with diabetes or ED.

How does tadalafil work (mechanism of action)?

Tadalafil has not been studied in patients with antidepressant-induced ED. No studies have directly compared tadalafil with sildenafil or vardenafil, but overall success rates have been comparable among the three options. The cost per dose of tadalafil is comparable to sildenafil or vardenafil and, if sexual activity is desired weekly, the cost is about $39 per month. As a result of its long duration of action, fewer doses of tadalafil may be needed, resulting in a small savings over time. The usual dose of tadalafil is 10 mg, cialis woman no more than once per day, taken orally at least 30 to 60 minutes before sexual activity. Tadalafil may cause a sudden decrease or loss of hearing.

Use Case	Description	Common Frequency
Erectile Dysfunction	Improve blood flow for erections	As needed, prior to activity
Pulmonary Hypertension	Off-label use for lowering pulmonary pressure	Prescribed under specialist care
BPH (Benign Prostatic Hyperplasia)	Sometimes prescribed for urinary symptoms	Off-label or combined therapy
Performance Anxiety	Enhances confidence in sexual activity	As prescribed by doctors

Stop taking tadalafil and tell your healthcare provider right away if you experience hearing loss or have any of the following symptoms. People who are allergic to any of the following should not take tadalafil.

Product introduction

The side effects may vary depending upon the condition being treated. Tell your healthcare provider if you have any of these side effects that bother you. Pain in your muscles, back, arms, or legs There may be other side effects of tadalafil that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at or by calling 800-FDA-1088. Any of the ingredients in the specific product dispensed Your pharmacist can tell you all of the ingredients in the specific tadalafil products they stock. Tadalafil should not be taken while you are using certain other medicines.

17.7 Sudden Hearing Loss

In Canada, you can report side effects to Health Canada at or by calling 866-234-2345. While less common, the most serious side effects of tadalafil are described below, along with what to do if they happen. Tadalafil may cause allergic reactions, which can be serious. Stop taking tadalafil and get help right away if you have any of the following symptoms of a serious allergic reaction. Swelling of the face, lips, mouth, tongue, or throat Itching, skin rash, or pale red bumps on the skin called hives Tadalafil may cause an unwanted erection that is persistent, painful, and that may occur without sexual arousal. Before taking tadalafil, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Interaction Partner	Effect	Clinical Advice
Alpha-Blockers	Increased risk of hypotension	Use caution, monitor blood pressure
CYP3A4 Inhibitors	Increased tadalafil levels	Dose adjustment may be needed
Alcohol	Enhanced side effects (dizziness, hypotension)	Limit intake during use
Ritonavir	Elevated plasma levels	Dose adjustment or avoidance

See the Interactions section for more details.

If you miss a dose, take it immediately.
Do not take two doses within 24 hours.
Resume your regular dosing schedule.
Do not take a larger dose to make up for it.
Keep a calendar to track your medication.
Inform your doctor if you miss doses.
Do not stop taking the medication.
Ensure you have enough medication for the month.
Missed doses can reduce effectiveness.
Do not take medication if you are allergic.

Do not take tadalafil unless it has been prescribed to you by a healthcare provider.

Cialis tadalafil 10 mg is also known as a daily or on-demand pill.
It provides a discreet solution for erectile issues.
The medication is usually well-tolerated by most men.
The effects can last longer than older ED medications.
Side effects are typically mild but can include gastrointestinal discomfort.
Always inform your doctor about existing medical conditions.
Use with caution if you have kidney or liver issues.
Don't mix Cialis with recreational drugs or unsafe substances.
Routine blood pressure monitoring is recommended during use.
Cialis can improve quality of life by enhancing intimacy.
Use the medication responsibly to avoid health risks.
Follow your doctor’s recommendations for optimal results.

Do not share tadalafil with other people, even if they have the same condition as you.

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including CIALIS. If you experience these symptoms, stop taking CIALIS and contact a healthcare provider right away. These are not all the possible side effects of CIALIS. For more information, ask your healthcare provider or pharmacist. Store CIALIS at room temperature between 59° and 86°F (15° and 30°C).

Cialis and foods

Keep CIALIS and all medicines out of the reach of children. Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. This is a summary of the most important information about CIALIS. For more information you can also visit or call 1-877-CIALIS1 (1-877-242-5471). CIALIS® (tadalafil) is a registered trademark of Eli Lilly and Company.