While less common, the most serious side effects of tadalafil are described below, along with what to do if they happen. Tadalafil may cause allergic reactions, which can be serious.
Cialis side effects
Do not take any more doses of tadalafil or similar medications such as sildenafil (Revatio, Viagra) or vardenafil (Levitra) until you talk to your doctor. Some patients experienced a sudden decrease or loss of hearing after they took tadalafil or other medications that are similar to tadalafil. The hearing loss usually involved only one ear and did not always improve when the medication was stopped. It is not known if the hearing loss was caused by the medication. If you experience a sudden loss of hearing, sometimes with ringing in the ears or dizziness, while you are taking tadalafil, call your doctor immediately.
Generic version
Call your doctor if you have any unusual problems while taking this medication If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088). Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Stop taking tadalafil and get help right away if you have any of the following symptoms of a serious allergic reaction. Swelling of the face, lips, mouth, tongue, or throat Itching, skin rash, or pale red bumps on the skin called hives Tadalafil may cause an unwanted free samples of cialis in canada erection that is persistent, painful, and that may occur without sexual arousal.
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Permanent damage to the penis may occur if priapism is not treated quickly. Stop taking tadalafil and get emergency help right away if you have any of the following symptoms of priapism.
16.2 Storage
For benign prostatic hyperplasia, tadalafil relaxes the muscles of the bladder and prostate, making it easier to urinate and reducing symptoms. Tadalafil should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. The most common side effects of tadalafil are listed below. The side effects may vary depending upon the condition being treated. Erection lasting for more than 4 hours Erection that is unrelated to sexual stimulation If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure. Tadalafil can cause mild, temporary vision changes such as seeing a blue tint, abnormal colors, blurry vision, or sensitivity to light.
- Can be taken with or without food for convenience
- Avoid high-fat meals to speed up onset
- Grapefruit juice can increase drug levels
- Alcohol in moderation is generally safe
- Excessive alcohol increases risk of side effects
- Caffeine may interact with some users
- Stay hydrated while using medication
- Do not use with recreational drugs like poppers
- Nitrates in some street drugs are dangerous
- Always inform doctor of all substances used
- Drug interactions can be life-threatening
- Keep a list of all medications for doctor
Though rare, some people have reported permanent vision loss. Stop taking tadalafil and get help right away if you have sudden vision loss in one or both eyes. Tadalafil may cause a sudden decrease or loss of hearing. Stop taking tadalafil and tell your healthcare provider right away if you experience hearing loss or have any of the following symptoms. People who are allergic to any of the following should not take tadalafil. Any of the ingredients in the specific product dispensed Your pharmacist can tell you all of the ingredients in the specific tadalafil products they stock. Tadalafil should not be taken while you are using certain other medicines. Before taking tadalafil, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details. Do not take tadalafil unless it has been prescribed to you by a healthcare provider.
How to use Cialis Tablet
You should carry the list with you in case of emergencies. Entadfi® (as a combination product containing Finasteride, Tadalafil) Tadalafil is a medicine that is commonly used for the following conditions. Erectile dysfunction, a condition where you have trouble getting or keeping an erection Pulmonary arterial hypertension, a condition where you have high blood pressure in the blood vessels that carry blood from your heart to your lungs Benign prostatic hyperplasia (BPH), a condition where the prostate gland has become enlarged Tadalafil may also be used for other conditions as determined by your healthcare provider. Tadalafil works by blocking the activity of an enzyme called phosphodiesterase 5 (PDE5). This enzyme usually stops some types of muscles from relaxing, including the muscles lining some types of blood vessels.
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By blocking PDE5, the muscles will relax and blood flow increases. For erectile dysfunction, it increases blood flow to the penis when aroused. This makes it easier to get and keep an erection. For pulmonary arterial hypertension, tadalafil relaxes the blood vessels in the lungs. This lowers blood pressure and reduces strain on the heart. Do not share tadalafil with other people, even if they have the same condition as you. Keep tadalafil out of the reach of children.
| Advice Topic | Recommendations | Rationale |
|---|---|---|
| Taking the Pill | Follow prescribed dosage and timing | Ensures safety and efficacy |
| Recognizing Side Effects | Report serious side effects immediately | Prevent complications |
| Combining with Other Meds | Always inform healthcare provider about current medications | Avoid adverse interactions |
| Post-use Care | Avoid driving or operating machinery if feeling dizzy | Ensures safety |
Sexual activity can put extra strain on your heart, which may be unsafe for people with certain health problems, such as a recent heart attack. Talk to your healthcare provider to see if your heart is strong enough for sex. If you feel chest pain, dizziness, or nausea during sex, stop and contact your healthcare provider right away. Tadalafil does not protect against sexually transmitted infections, including HIV.
- Store in original packaging to protect from moisture
- Keep in a cool, dry place away from heat
- Do not store in bathroom or near sink
- Avoid freezing or extreme temperatures
- Check for discoloration or damage before use
- Dispose of expired or unused tablets properly
- Use drug take-back programs if available
- Do not share with others, even if symptoms similar
- Keep out of reach of children and pets
- Travel with medication in original labeled container
- Carry a copy of prescription when traveling abroad
- Check local laws if traveling internationally
Tadalafil belongs to a group of medicines, known as phosphodiesterase-5 (PDE-5) inhibitors, which are used to treat erectile dysfunction or pulmonary arterial hypertension.
How to take it
Tell your healthcare provider if you have any of these side effects that bother you. Pain in your muscles, back, arms, or legs There may be other side effects of tadalafil that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at or by calling 866-234-2345. You should not take more than one PDE-5 inhibitor medicine. Medicines in this group include avanafil (Stendra), sildenafil (Viagra, Revatio, and others), tadalafil (Cialis and others), and vardenafil (Levitra, Staxyn). If you take liquid tadalafil, shake the bottle well for 30 seconds before use. Use an accurate measuring device to measure your dose. A household spoon is not an accurate measuring device and may cause you to take the wrong dose. Ask your pharmacist to recommend an appropriate measuring device. Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if tadalafil is right for you.
In Case of Any Issues Contact Us
Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of cialis online pharmacies Medicines website for more information. Keep all medication out of sight and reach of children as many containers are not child-resistant. Place the medication in a safe location – one that is up and away and out of their sight and reach. In case of overdose, call the poison control helpline at 1-800-222-1222.
Allergy warning
Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. In particular, make sure that you discuss any of the following.
| Condition | Optimal Range | Notes |
|---|---|---|
| Temperature | 20°C to 25°C | Keep away from heat |
| Humidity | Below 60% | Protect from moisture |
| Light | Store in original container, out of light | Protect from light |
| Children | Keep out of reach | Safety measure |
Tell your healthcare provider if you have any of the following.
5.10 Concomitant Use of Potent Inhibitors of Cytochrome P450 3A4 (CYP3A4)
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine. If you are taking tadalafil for erectile dysfunction on a regular schedule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose or more than one dose per day to make up for a missed one. If you are taking tadalafil for PAH or BPH, take the missed dose as soon as you remember it.
How does tadalafil work (mechanism of action)?
Do not take a double dose to make up for a missed one. pain in the stomach, back, muscles, arms, or legs sudden decrease or loss of vision (see below for more information) changes in color vision (seeing a blue tinge on objects or having difficulty telling the difference between blue and green) sudden decrease or loss of hearing (see below for more information) erection that lasts longer than 4 hours swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs Some patients experienced a sudden loss of some or all of their vision after they took tadalafil or other medications that are similar to tadalafil. The vision loss was permanent in some cases. It is not known if the vision loss was caused by the medication. If you experience a sudden loss of vision while you are taking tadalafil, call your doctor immediately or get emergency medical treatment. Heart problems, such as heart rhythm problems, chest pain, or heart failure Heart attack, stroke, or heart surgery within the past six months High blood pressure that is still too high despite taking medicines for it Peyronie's disease, or a penis with an abnormal curve or shape An erection lasting longer than four hours A blood disorder, such as sickle cell anemia, multiple myeloma, or leukemia An inherited eye disease called retinitis pigmentosa Vision loss, or a problem with the nerve between your eyes and brain (optic nerve) Health conditions or factors that raise the risk of optic nerve problems, such as diabetes, high cholesterol, smoking, being older than 50, or having a “crowded disc,” which is something an eye doctor may see in an eye exam Pulmonary veno-occlusive disease, a condition where blood vessels in the lungs are blocked It is not known if or how tadalafil could affect pregnancy or harm an unborn baby.
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